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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4afab36b8044137f0bdfc5543ecde731191adcb0857eda9886d20dc160a40051' 
  AND token = 'ehXJNj7GXvvAdW9deS3AN/w7UV381JjSUYLem9vqXLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}