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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81ca0c613e018c1b301afce7c7d55ce52979f006c14da2a5686a98ab8100177' 
  AND token = '0PzrDruAR7XgGQ8S/wbZy+Mop54HA0LMWKi97seaBR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}