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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1ca338fe2aaeebd5d4f700755d790e7ae725b4e19011dcbd1631f1da3707b17' 
  AND token = 'oa+G5lZL4dhPfQGeLoiSFKPyKt8c5JGldQ4wzu4bfNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}