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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e8dce21a233613335a501080bb56f18f5db6a110fe30ab1fdcbf0feac3508a3' 
  AND token = 'zj0UleAxgK0d+RpYdscoqZWK6f911c+tAFne2QxDtKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}