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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b9c4bc2c3c491134ecc58f7556c50a95c10f53f36dca9129f20d5ed49bbea1c' 
  AND token = 'QdAv80SfYX1hd9zmltLHh55wY+wSZfddk2JMVUy6UDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}