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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cf3270273386e44959a8d2611847bdaebceaab86d55b8a92c9f1287193badac' 
  AND token = 'LKDV6JfQDxByw1R27kdOB0LuI5HlCXI3qe6esDQCdkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}