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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be4a38f36fd555fbf3c03acae28f952baae69d8b4e26fc9f7c68d79171a5c760' 
  AND token = 'FvnOWnVIqjIg6OSFBVQbaN4gKvFcLi4tNJMA+zDSNdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}