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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05f9bb8ac94d9a5052bb0bdacebbee5fbd5a6b5d871d09580699c363f325f289' 
  AND token = 'DZBBiDdtRqETe87yJzxYpN7te9WLd9ZckLDKUHb2K9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}