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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34d06fd61edcc7500a8a7f2dad86b214f80bfdc653ddc4c53ec11654ced8870c' 
  AND token = 'Z6qARbVGPuPq7V32ZBSI6+5fyPn4hsUOdim0sT3MNRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}