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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d527b0514672e66560262e2dd7fcfdb69a7ca7569051014684b1713a012dd93' 
  AND token = 'Pph6FXgs+5LgHYhU36mPmLP7HeFLxxR3etXWSDGULC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}