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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2075ceb7f1b1460ed4b32697c650cbcdc65dcb003c109287bbe49068d0cc8f50' 
  AND token = 'VwzJMsu7QGaVb+gl60+Nlh7/CPy9Dm1qsSIGbF0ilF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}