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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '855619da88590a26d9daa31dd7b1de78cba628547ddbaaa3de6c96e7fbadce47' 
  AND token = 'qtAQsnzqfLTE2YM3ZJ/Jucu7JEzJL8bmPi9Fva5hVm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}