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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2de0167ea9cdf5939e2f7e6a71f24dcc1016ad61673bb6094bd0c4b8d5ffedb' 
  AND token = 'lQNJ425PmtdCMEGK30YznqKwtUhs5SzrjbF3cl7tECE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}