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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6331666f0cf0a3b47bfc240a28ce9c42f68f49140bc5001a73548eed440c7efe' 
  AND token = 'I0TwY9MZdTgEiBVRnMwDI9iabbsrRot+9u3JhTtGG/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}