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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a520d0f4ff30f6b7f276305da36db4edeeb014641f0af5c588ca6da7c51a1e' 
  AND token = '/dcESSmxw4yomryL7VMbI6IO3jibv1RCyXnWIVGH4gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}