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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '012499024620a0f2d647e78011ea61743792c2f58faa5b4ee6bfef98464c453c' 
  AND token = 'aTcLoUvjkTgdUUFL4UZOqc9kwEYK15YcPcOKabORHtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}