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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0526d1e888b01326f52c8826693cfb01c3891da2c644980d98bd243b502fa702' 
  AND token = 'jD0msSGJNOSYiP8s9i4HzLicihV9pkpX1/nDm+k2ZUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}