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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4184da13f7f54834f8f1136d3c1b6adb23606f4ecb49f80ff54e9abaa792a1f1' 
  AND token = 'uTOX1kfiFb8St9BqrsISLU+6aGFrELOdeQ/amel27ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}