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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c41c4880ae96f37488fa86b5e7300605dbc7d92d29aef0e7482033c14b8020' 
  AND token = 'vDWp55pQRFOuEPruoahUDB0gjp6cMJ3mON7t1ametMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}