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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72896fcf21c96d761dbcc68e5e7e06c16314422bc29a6dd87eca89bf9f71383a' 
  AND token = '1pCairpcuua54HwTwmlvw6DqEAtLZmqsvC+PDUPUncg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}