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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff2def6f0ecba1094013e13de35a3ed23ce5a20473a72822c647d306fb1ae66' 
  AND token = 'dmpOI3KN9PbL5+Vzf8hG3JYM0UBo4KYiad3JXGGKCvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}