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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd70fc20ebc90afc5f2dced0d4eeab0b4938fc51d666456fe527b33a111e851' 
  AND token = 'ya8v2Ot/Lg4f+jOw3kQdxNwJQMvDUsw+OXKPxDWkYtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}