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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65cb806868f48a3cd2953edf76998bd611432b7a6856fcf3080078dea64c0da' 
  AND token = 'cXVi0a5LSRa6J89TsDoMMk6v6pdJp/tYxS9jT+1ZQXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}