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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ffc7a924c6c7309e6839f3c8713f07e9cce49543f9cc3571d3519ecd41a677' 
  AND token = '5NZyWsWUUZn5U+H5TBptNOIp3aHVq9KPho0t557d+7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}