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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5080ec669d92075e877eba71549b1225e597e987834d458d08d013ccd72f87ac' 
  AND token = '6i3vCi7as51ReFQpSY/1/JDOpUu0lP5itXK2u0DkB/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}