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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a05c9b9c5b5a549c4825f015a95fc7e7a2c98b19b25e3e91a5134070e3f1e9a4' 
  AND token = '1zaW/+zEr7syBCkA6cU7lo74xz7yR1y1wW0YX8Zq27I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}