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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a6f03f25df14cfd10d0d78c6a11f9a9760dffde1e174c1d1a1591d6eebbe1b6' 
  AND token = 'XeCywWVYu8SoEaR9mtewlJuiZdCzNR2nCLQfG73XEvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}