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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aaacb3e54e8dca51413b52eec25f1c16ddf2794f15222d8899c9d3d1d592d7f' 
  AND token = 'kj7DvQMs/duGqGFeJ6JNCn70e1BIGZ3qSsFGldQ81jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}