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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '892c3cccfba541591149ccdbedbd8f76f8361d37f6fd5843b03c7fbd116c325c' 
  AND token = 'JCz1XcryuJq+WSitF8vI6br14cBm+mpPn2jhtxJPNc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}