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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fe1d4e8242b4cf91900ee562d61fcc4f3efe865f7a5e0c5187fb0be7ea71359' 
  AND token = 'kfxbFNi6Kg7WiF5IJkwKV7fGdgdVmBdgYxann9XkDOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}