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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b921e8d96300d8b522bff5e5842283a3e84ea3ee71a42d1301bda9f1920877cf' 
  AND token = 'fZCefr2oVbD1MVamUtXzI7rO6IPS3z7nm5ZbgJ8hbLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}