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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2dd6410fda3fac146f5e3f6b3d41a8dbce91df1a9add8e38796f23be5122966' 
  AND token = '4m6ZfddxdbsWsoqNAHgfjGV4HWfEDzXS1BOHYs7RMSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}