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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df056d3a1d9b0feece027cd7ff881c91f92a9605f2aa57b97d8c2d240f1f529c' 
  AND token = 'KbwwTm56dlEioOfVMxrxdgDdaDGFnN4wpt9mXK8v5Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}