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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c284578a3747cc0378d29ffe614fd50ea7bcd95b51bc1b0ec20d35a3a459714' 
  AND token = 'zCxxyRrdZ9CeCdUfevpqQls7yHKzRK7SOPL1kuqboQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}