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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b182277477f9bc96ca403b1e8f2863c855c0c390082e60316786b028f10cae97' 
  AND token = 'ZfyzbS4TJd5nu4S+Er7XmjldmJIu88W1tmVXVV37cQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}