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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f321ec1e7fbf6d41210d0d4e390519b9342be70705f0b338decd22005bcd5091' 
  AND token = '3I/TPbN4VnNiKxhb0QzWD/O/togbtM+xkMHKT7sqZy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}