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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b57439ce1c4936ff4064c6df49060dfec5aa921dfcd7e1211d4fb5ae4f19a054' 
  AND token = 'Qi0TZCAcqnoUvFUY88OHo5hiqxYrU6ZIXTf9O6Vp9NU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}