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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89867f6d3180cf0880bc3220870b5356a17c4f56788e93e43197906f39e19fa0' 
  AND token = '2xa+p8feaYPWeOq2GTI8EAOK+sW3adXlLo/pZCNwrHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}