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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29205a82e641293939840b33768d7d2c705fc3c32291602d7e9f124a0161b43e' 
  AND token = 'FUE0gSUV1KFQnQk20rkqA6h/qZIUC9Py08SSNw15Vv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}