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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca324f7509640121c764a7be36feb4db450fc9c4190f8fe9b325daca1690c26f' 
  AND token = 'vC6q17RGF+731GkmeBaKs9uv8+kAf4HsePWDH6Vtuqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}