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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf419ce0586eb523e8a8d9b8afefbe17f638b30cbbed003480c183d2d2f07f28' 
  AND token = '9wXyJeD2GjBCkIG9MX+xNp+U3mKYvLEp9V9lH0HpuAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}