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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fce6b78c3de647ccd4e68bd4d56c30dd5b69c2cd5332a7ccdae8d5c92a35043' 
  AND token = 'ODIAyrEHLkHEa3TrWn82MYlDzQ+i8wlzw3xOmRiKkAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}