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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78abbc8ade8e12c4d676d9d05fb9472a6d961ff51eddd796731464eb821f6a2' 
  AND token = 'gWzE69Tuf5cFXuvmLeghICTuNnWMwGTaE5QFCJ4O9xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}