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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f097fe5177963e32dcf3439a35a712792eebb0915e3019e0ad2070b7270f32a' 
  AND token = 'R6zfno0HsKIa+IqQJMt7oQ0Pgwm0skyuI9208UBxKZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}