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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50eb8b1314448c31aba953cefaef4d8a4cf4c47441e86155ed5a0697b958c16' 
  AND token = 'ziJUmQJmCFjtF6tKaBebqxWgpwekAoyPSni5k9cddkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}