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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb1edf0f852acd80ba32bf7f0ef43cd6f796cdbde4ad6e3f1f48f79b09280332' 
  AND token = '8G3OUNW1ihieTJ+zUNyERoXkBYvcVjEF24NdlaLD0dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}