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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8975666afe9f2fd0bacd46540e1d9351536304310f5004e548b44eb30fa18673' 
  AND token = 'NdVGMt4hh42iIxaysgZTo+kyjYDpZiJolmcd6Ny1x5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}