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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b3f3df58624eb883eae2a1811efb7ae14ffee653ee43904522d5fadc40abe6' 
  AND token = 'S00sN7vfc9x43pqGyC8VuujDkKO3iBlohENlajKO0Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}