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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33713c6a59af63f86316851a1c6e0f15f619e1b7d50730c7f0e0e295a5f0905a' 
  AND token = 'Ws3PQcnsQ/9GfC12m85FgGEzHQdplIExe4Ei0ZUQEtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}