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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0805fa4c9c45bc858c4b6e697e236dc88e16be2f065645398d67d203483003ff' 
  AND token = 'TYaSYYWb1fpB2wGZ0RN+zUWUocwn2S3K1uwvLrny15Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}